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CJC-1295/Ipamorelin

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CJC-1295/Ipamorelin: Growth hormone–releasing peptides that promote fat loss, muscle growth, deeper sleep, and anti-aging.

⭐⭐⭐⭐⭐Boosts Growth Hormone 5x

Potential Benefits of CJC-1295 + Ipamorelin

Physiologic GH Support

Combines a GHRH analogue (CJC-1295) with a ghrelin-receptor agonist (Ipamorelin) to encourage pulsatile growth-hormone release rather than direct GH replacement.

Sleep, Recovery & Vitality

Commonly used in programs that target deeper sleep, post-training recovery, and general vitality—paired with nutrition and training.

Body-Composition Support

When combined with diet and exercise, may assist lean-mass maintenance and fat-loss efforts.

Important: Compounded peptides are off-label for adults and not FDA-approved for anti-aging or weight loss. Human evidence is limited. Use only under supervision of a licensed clinician.

Contraindications & Precautions

Contraindications

  • Known hypersensitivity to CJC-1295, Ipamorelin, or formulation excipients

  • Pregnancy or breastfeeding

  • Active malignancy (or history of cancer without verified remission)

Use with Caution

  • Diabetes or impaired glucose tolerance — clinician may monitor glucose/A1c

  • Thyroid or pituitary disorders — specialist oversight recommended

  • Cardiovascular, hepatic, or renal disease — coordinate with prescriber

  • Fluid-retention symptoms (edema, carpal-tunnel-like paresthesia) — adjust or discontinue if needed

  • Concurrent GH-axis therapies or weight-management drugs — avoid stacking without guidance

Results, Dosing & Side Effects

Typical Program Goals

  • Support healthier sleep architecture and recovery

  • Assist body-composition plans alongside diet and exercise

  • Promote wellbeing/energy when clinically appropriate

  • Individualized targets set by clinician and labs

Dosing & Administration

  • Route: Subcutaneous injection (often evening); rotate abdomen/thigh/upper arm sites

  • Schedule: Nightly or cyclical protocols per clinic; some combine both peptides in one session

  • Monitoring: Clinician may track IGF-1, metabolic markers, sleep metrics, and symptoms

Exact dose and frequency are individualized. Follow your provider’s instructions.

Side Effects — Common

  • Injection-site redness/itching or bruising

  • Flushing, lightheadedness, headache

  • Nausea, transient fatigue, vivid dreams

  • Temporary water retention, joint/tunnel-like tingling

  • Appetite changes (ghrelin-related with Ipamorelin)

Side Effects — Monitor/Serious

  • Worsening glucose control — contact your provider

  • Significant edema, palpitations, or chest pain — evaluate promptly

  • Allergic reactions (rash, swelling, breathing difficulty) — seek care

Why Choose CJC-1295 + Ipamorelin?

This combo engages two complementary GH pathways: CJC-1295 (GHRH analogue) cues the pituitary to release GH in a physiologic, pulsatile manner, while Ipamorelin (ghrelin-receptor agonist) enhances that signal with minimal cortisol/prolactin overlap compared to older secretagogues.

Patient Story:
“Within a few weeks, my sleep felt deeper and workouts recovered faster. Pairing the injections with a clean diet made the difference.” — Avery S.

Mechanism of Action

  • GHRH Receptor Agonism (CJC-1295): Stimulates pituitary GH release; encourages downstream IGF-1 in a physiologic pattern

  • Ghrelin Receptor Agonism (Ipamorelin): Amplifies GH pulses with selective pituitary action

  • Pulsatility: Seeks to preserve natural GH rhythm vs. flat replacement

  • Program Fit: Best used with sleep hygiene, resistance training, protein-forward nutrition, and clinician monitoring

Educational content only. Peptide programs should be supervised by a licensed healthcare professional and individualized to the patient.

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