Glutathione

Potential Benefits of Glutathione (GSH)

Cellular Antioxidant Defense

Endogenous antioxidant that helps neutralize reactive oxygen species and supports redox balance.

Liver & Detox Pathways

Cofactor in phase-II conjugation pathways; often used to support hepatobiliary wellness programs.

Skin & Immune Support

Frequently incorporated for complexion support and immune wellness; evidence varies by indication.

Important: IV/IM glutathione is not FDA-approved to diagnose, treat, cure, or prevent disease. Outcomes vary; use only under a licensed clinician’s supervision.

Contraindications & Precautions

Contraindications

• Known hypersensitivity to glutathione or formulation excipients

• Pregnancy or breastfeeding (insufficient safety data)

• Active severe illness unless managed by the treating specialist

Use with Caution

• Asthma or history of bronchospasm (especially with inhaled GSH)

• Sulfite sensitivity or significant allergy history

• Renal/hepatic impairment — adjust plan per clinician

• Concurrent chemotherapy or investigational therapies — coordinate with oncology before use

• Monitor if prone to hypotension, migraine, or nausea during infusions

Outcomes, Dosing & Side Effects

Reported Outcomes

• Support for oxidative-stress balance and recovery routines

• Adjunct to liver wellness protocols (diet, hydration, exercise)

• Skin tone/brightness programs in some clinics (evidence mixed)

• Best results occur with nutrition, sleep, and lifestyle alignment

Dosing & Administration

• Route: IV infusion or IV push; IM/SC per prescriber

• Rate: Infuse slowly to reduce flushing, chest pressure, or nausea

• Frequency: Series then maintenance per clinic protocol and patient response

• Hydration: Encourage fluids; monitor vitals during infusion

Exact dosing is individualized. Follow your clinic’s protocol and clinician guidance.

Side Effects — Common

• Warmth/flushing, metallic taste

• Nausea, lightheadedness, headache

• Injection/infusion-site irritation

• Transient fatigue post-infusion

Side Effects — Serious/Rare

• Allergic reactions (rash, pruritus, anaphylactoid symptoms)

• Bronchospasm (more likely with inhaled GSH) — stop and evaluate

• Marked hypotension or chest discomfort — stop infusion and assess

Why Choose Glutathione?

Glutathione is a tripeptide (glutamate, cysteine, glycine) central to redox balance and cellular defense. Carefully titrated programs may help clients seeking antioxidant support as part of comprehensive care.

Patient Story:
“A few sessions in, I noticed steadier energy and less post-workout soreness. The slower infusion pace made treatments very comfortable.” — Riley M.

Mechanism of Action

• Antioxidant System: Reduced GSH donates electrons to neutralize peroxides via glutathione peroxidase; regenerated by glutathione reductase

• Detox Conjugation: Substrate for glutathione-S-transferases in phase-II metabolism

• Vitamin Cycling: Helps recycle oxidized vitamins C and E

• Administration: IV/IM protocols under clinician supervision; rotate injection sites and monitor vitals

Educational content only. Glutathione services should be delivered under licensed medical supervision and individualized to the patient.