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Sermorelin

Growth hormone–releasing hormone (GHRH) analog for stimulating natural growth hormone production and supporting healthy aging

⭐⭐⭐⭐⭐Natural HGH Optimization

Potential Benefits of Sermorelin

Physiologic GH Support

Stimulates your pituitary to release growth hormone in a natural, pulsatile pattern rather than replacing it outright.

Sleep & Recovery

Commonly used to support deeper sleep, post-training recovery, and overall vitality when paired with healthy habits.

Body Composition Support

When combined with nutrition and exercise, may help lean-mass maintenance and fat-loss programs.

Important: Compounded sermorelin is used off-label in adults. It is not FDA-approved for anti-aging or weight loss. Use only under a licensed clinician’s supervision.

Contraindications & Precautions

Contraindications

  • Active malignancy or history of cancer without confirmed remission

  • Known hypersensitivity to sermorelin acetate or formulation excipients

  • Pregnancy or breastfeeding

Use with Caution

  • Diabetes or impaired glucose tolerance — monitor glucose/A1c

  • Thyroid or pituitary disorders — evaluate underlying endocrine status

  • Fluid retention symptoms (edema, paresthesia) — adjust or discontinue if needed

  • Concurrent use with other GH-axis therapies — specialist oversight recommended

Results, Dosing & Side Effects

Typical Goals in Programs

  • Support healthy sleep architecture and recovery

  • Assist body-composition plans alongside diet and exercise

  • Promote wellbeing and energy when clinically appropriate

  • Individualized targets based on labs and clinician guidance

Dosing & Administration

  • Route: Subcutaneous injection, commonly in the evening

  • Schedule: Nightly or cyclical per prescriber’s protocol

  • Sites: Abdomen, thigh, or upper arm — rotate sites

  • Follow labs: Clinician may monitor IGF-1 and metabolic markers

Dosage is individualized. Use only as directed by your licensed provider.

Side Effects — Common

  • Injection-site redness or irritation

  • Flushing, headache, lightheadedness

  • Nausea, transient fatigue

Side Effects — Monitor/Serious

  • Edema, paresthesia, carpal-tunnel–like symptoms

  • Changes in glucose control

  • Allergic reactions (stop and seek care)

Why Choose Sermorelin?

Sermorelin (a GHRH analogue) works with your pituitary to stimulate your own growth hormone production, supporting a physiologic, pulsatile GH pattern rather than direct hormone replacement.

Patient Story:
“Within a few weeks I noticed deeper sleep and better recovery after workouts. My overall stamina feels improved.” — Naomi S.

Mechanism of Action

  • GHRH Receptor Agonism: Binds pituitary GHRH receptors to trigger endogenous GH release

  • Physiologic Pulsatility: Encourages nightly GH pulses and downstream IGF-1 production

  • Metabolic Effects: GH/IGF-1 pathway supports tissue repair and body-composition programs

  • Administration: Subcutaneous injection; rotate sites and follow clinician guidance

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