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GHK-Cu

GHK-Cu: Clinically shown to boost collagen, repair tissue, and reverse visible signs of aging.

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Skin Firmness & Smoothness

Supports the appearance of collagen/elasticity and helps soften the look of fine lines and texture.

Post-Procedure Comfort

Used after cosmetic treatments (per clinician guidance) to support barrier comfort and visible recovery.

Scalp & Hair Appearance

Common in scalp routines to support the look of thicker, healthier-looking hair.

Contraindications and Precautions

Contraindications:

  • Known allergy to copper, GHK-Cu, or formulation excipients

  • Pregnancy or breastfeeding (insufficient safety data)

  • Active skin infection/open wounds unless specifically directed by your clinician

Use with Caution:

  • History of contact dermatitis or very reactive/sensitive skin — patch test first

  • Copper-metabolism disorders (e.g., Wilson disease) — discuss with your provider

  • Concurrent copper supplements or chelation therapy — coordinate with your clinician

  • Periocular use — avoid eye contact; rinse thoroughly if exposure occurs

  • Immediately post-procedure — follow your clinic’s specific timeline and instructions

Results, Dosing, and Side Effects

Reported Results:

  • Visibly smoother, more elastic-looking skin with regular use

  • Improved look of tone and texture; supports barrier comfort

  • Complementary in hair/scalp routines for fuller-looking hair

  • Best results when paired with sun protection, nutrition, sleep, and consistent skincare

Dosing and Administration

Route: Topical (serum/cream/solution). In-clinic protocols may include microneedling/mesotherapy per prescriber.

  • Frequency: Often once or twice daily, or as directed by your clinician.

  • How to Apply: Cleanse → apply GHK-Cu → moisturize. Use sunscreen in the AM.

  • Layering Tips: To reduce irritation and potential peptide degradation, avoid immediate layering with strong acids, benzoyl peroxide, or high-strength retinoids.

  • Storage: Keep capped, away from light/heat. Blue color may lightly tint fabrics/products.

Follow your clinic’s exact concentration and schedule. Cosmetic/topical use only unless directed by a clinician.

Side Effects — Common

  • Mild stinging, redness, dryness, or tightness after application

  • Temporary irritation on sensitive areas or after procedures

  • Rare light blue tint on skin or fabrics from the copper complex

Side Effects — Serious (Rare)

  • Allergic contact dermatitis (rash, swelling, intense itch) — discontinue and seek care

  • Significant eye irritation if product enters eyes — rinse and evaluate

  • Unusual systemic symptoms — stop and contact your clinician

Why Choose GHK-Cu?

GHK-Cu is a naturally occurring tripeptide (glycyl-L-histidyl-L-lysine) that binds copper. In aesthetic skincare, it’s used to support the look of healthy collagen, elasticity, and barrier comfort while adding a subtle antioxidant/soothing effect. Many patients like it as a gentle, cosmetically elegant option.

Patient Note:
“After 8 weeks, my skin feels calmer and makeup sits better—especially around fine lines.”

Patch Test & Routine Tips

  1. Apply a small amount behind the ear or inner forearm.

  2. Wait 24–48 hours. Mild warmth is possible; stop if rash, swelling, or severe itch occurs.

  3. If clear, begin regular use per your plan.

  • Separate from strong acids/retinoids if irritation occurs (e.g., GHK-Cu AM, actives PM).

  • Avoid immediate application before contact with light-colored fabrics.

  • Do not share products; keep away from children and pets.

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